Bheki Mamba is the president of the Swaziland Democratic Nurses Union, a nursing organisation acting as the sole negotiating body for nurses on labour and professional issues in Swaziland. He has participated and still serves in many policy formulation committees and ad hoc task teams within the health sector and the entire public sector.
In 2010 he was elected to serve as the chairperson of the Southern Africa network of nurses and midwives (SANNAM). This is a regional network representing 15 NNAs in the SADC region dealing with professional, policy and socio-economic issues for nurses and midwives at a regional perspective.
In 2008 he was seconded by the Ministry of Health to head the epidemic unit under the National Emergency Preparedness and Response department. Before that he has worked in several public health facilities in the country.