[Excerpt from authors] Developing and implementing a comprehensive ergonomic plan is the right thing to do, especially when a nursing shortage exists. The American Nurses' Association (ANA) Handle With Care campaign addressed the fact that 12% of RN turnover and 38% of RN workers' compensation pay are related to back strains. The average cost to replace a RN related to workers' compensation ranges from $25,450 to $38,280 using the ANA Handle With Care findings as a benchmark. Health care worker injury prevention should be valued as a retention strategy as well as a fiscal responsibility where all stakeholders benefit.